To determine the role of positive and negative emotion, pessimism, optimism, and information processing styles in the students’ psychological adjustment, using the multi-stage cluster sampling method, 400 students of Tabriz University were selected. They were assessed by the positive and negative affect scales (PANAS), Life Orientation-Revised (LOT-R), California Psychological Test (CPI), and Perceive Modes of Processing Inventory (PMPI). The data was analyzed using multiple regression and Pearson correlation coefficient methods. Findings showed that optimism, positive emotions, and rational and experimental information processing styles could significantly predict the psychological adjustment. Therefore, the present study suggests that the students’ psychological adjustment is considerably influenced by their emotional, attributive, and cognitive factors, so these parameters can affect their process of Psychological adjustment.