Volume 9, Issue 4 (volume9, Issue 4 2022)
JCP 2022, 9(4): 35-53 |
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Hallajian A, Dehghani-Arani F, Rostami R, Bayat M , Rahmati Y. The role of temporo-parietal junction on implicit mentalizing in autism spectrum disorder: a theta-burst stimulation study. JCP 2022; 9 (4) : 50
URL: http://jcp.khu.ac.ir/article-1-3483-en.html
URL: http://jcp.khu.ac.ir/article-1-3483-en.html
University of Tehran , f.dehghani.a@ut.ac.ir
Abstract: (3767 Views)
The temporo-parietal junction is a key region in the theory of mind process. Numerous brain imaging studies have demonstrated its involvement in the mentalizing process and its under-activation in autism. This study aimed to investigate the causal relationship between rTPJ activation and implicit mentalizing in autism spectrum disorder. This study is a single-blind Quasi-experimental study with a repetitive measures design. Nine children and adolescents with autism were recruited by convenience sampling method using Gilliam autism rating scale (GARS), Social Responsiveness Scale (SRS), and Stanford-Binet (SB). Afterward, they were assigned to three randomly ordered stimulation sessions: cTBS, iTBS, and sham. Immediately after each session indexes related to the subject’s implicit mentalizing were measured by a computer-based task. Repeated-measures ANOVA results demonstrated that the active stimulation sessions improved implicit mentalizing compared to sham sessions. It seems that there is a causal relation between rTPJ activation and implicit mentalizing.
Article number: 50
Keywords: Autism Spectrum Disorder, Theory of mind, Theta-burst stimulation, Temporo-parietal junction
Type of Study: Research |
Subject:
Psychology - Clinical Neuropsychology
Received: 2021/09/11 | Accepted: 2022/02/2 | Published: 2022/02/6
Received: 2021/09/11 | Accepted: 2022/02/2 | Published: 2022/02/6
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