Performance of adolescents with major depressive disorder and PTSD in working memory and processing speed

Authors
kharazmiunivercity
Abstract
The present research aims to compare the cognitive performance of the adolescents suffering from MDD and PTSD in the working memory and information processing. the selected sample in this casual-comparative study included 15 MDD patients, 15 youth PTSD subjects and 15 normal subjects who were matched by age, IQ, sex as well as social and economic status variables. The tool package employed in this investigation comprised child depression inventory (CDI), State-Trait Anxiety Inventory, Impact of Event Scale (IES-R), Wechsler’s Memory and Intelligence Test, and The Information Processing Index Test. Findings were analyzed using the ANOVA, MANOVA analysis statistical method.as indicated by our result, in the verbal memory there is a significant difference between groups of depression and PTSD and between depressed and normal subjects. in the reverse spatial working memory there are significant differences between normal and PTSD. in the visual memory and information processing, the significant difference is between normal and both PTSD and depressed.The findings of this study confirm the disorders of working memory and speed of information processing in adolescents with depression and post-traumatic stress disorder.
Keywords

Bremner, J. D., Narayan, M., Staib, L.H., Southwick SM, McGlashan T. & Charney DS., (1999). Neural correlates of memories childhood sexual abuse in women with and without posttrumatic stress disorder. J Psychiatry, 156, 1787-1795.
Brooks, B. L., Sherman, E. M. S., & Lverson, G. (2010).Identifying cognitive problems in children and adolescents with depression using computerized neuropsychological testing. Applied Neuropsychology, 17(1), 37-43.
Burt, D.B., Zembar, M.J., Niederehe, G.M, & Ellwanger, J. (2000). Depression and memory impairment: a meta-analysis of the Caligiuri,). Motor and cognitive aspects of motor retardation in depression. Journal of Affective Disorders, 57,83-93.
Ellis, H. C., Ashbrook, P. W. (1988). Resource allocation model of the effects of depressed mood states on memory. In K. Fiedler J. Forgas(Eds.), Affect, cognition, and social behavior: New evidence and integrative attempts, 25-43.
Fann, J. R., Uomoto, J.M., & Katon, W.J. (2001). Cognitive improvement with treatment of depression following mild traumatic brain injury. Psychosomatics, 42(1), 48-54.
Galletly, Ch.,Clark, C. R.,McFarlane, A. C., & Weber, D. L.(2001). Working memory in posttraumatic stress disorder—an event-related potential study. J Trauma Stress, 14(2), 295- 309.
Gotlib, I. H., & Joormann, J. (2008). Updating the Contents of Working Memory in Depression: Interference From Irrelevant Negative Material. Journal of Abnormal Psychology, 117(1), 182-192.
Gu¨nthera, K T. H., Jolles, H. J., Herpertz-Dahlmanna, B., & Konrad, K. (2004). Verbal memory and aspects of attentional control in children and adolescents with anxiety disorders or depressive disorders. Journal of Affective Disorders, 82, 265–269.
Guyer, A. E., Choate, V. R., Grimm, K. J., Pine, D.S., & Keenan, K. (2011). Emerging depression is associated with face memory deficits in adolescent girls. J Am Acad Child Adolesc Psychiatry, 50(2), 180-190.
Horan, W. H., Pogge, L. D., Borgaro, R. S., Stokes, M. J., & Harvey, D. P. (1997). Learning and memory in adolescent psychiatric inpatients with major depression: A Normative Study Of the California Verbal Learning Test. Archives of Clinical Neuropsychology, 12(6), 575-584.
Jemeleddine, E., Bouden, A., Halayem, S., Othman, S.,Tabbane, K., Halayem, M. (2009). Memory impairments during child and adolescent depression. Journal of La tunisie Medicale, 656-659.
Johnsen, G. E., Kanagaratnam, P., & Asbjørnsen, A. E. (2008). Memory impairments in posttraumatic stress disorder are related to depression. Journal of Anxiety Disorders, 22, 464–474.
Kalb, K., Do¨ rner, M., & Kalb, S. (2006). Opposite effects of depression and antidepressants on processing speed and error rate. Neuro-Psychopharmacology & Biological Psychiatry, 30, 244-250.
Kira, I., Lewandowski, L., Somers, C. L.,Yoon, J. S., & Chiodo, L. (2012). The effects of trauma types, cumulative trauma, and PTSD on IQ in two highly traumatized adolescent groups. Psychological Trauma: Theory, Research, Practice, and Policy, 4(1),128-139.
Matthews, K., Coghill, D., & Rhodes, S. (2008). Neuropsychological functioning in depressed adolescent girls. Journal of Affective Disorders, 111, 113–118.
Moradi A. R., Herlihy J., Yasseri G., Shahraray M., Turner S., &Dalgleish, T. (2008). Specificity of episodic and semantic aspects of autobiographical memory in relation to symptoms of posttraumatic stress disorder (PTSD). ActaPsychologica, 127, 645-653.
Moradi, A. R.,Taghavi, R., Neshat-Doost, H.T.,Yule, W., & Dalgleish, T. (2000). Memory Bias for Emotional Information in Children and Adolescents with Posttraumatic Stress Disorder: A Preliminary Study. Journal of Anxiety Disorders, 14(5), 521–534.
Nebes, R.D., Butters, M.A., Mulsant, B. H., Pollock, B.G., Zmuda, M.D., Houck, P.R., Reynolds, C,F.(2000). Decreased working memory and processing speed mediate cognitive impairment in geriatric depression. Psychological Medicine, 30, 679–91.
O'Connor, D. W., Pollitt, P. A., Roth,M., Roth,M., Brook, P. B. & Reiss, B. B. (1990). Memory complaints and impairment in normal, depressed, and demented elderly persons identi®ed in a community survey. Archives of General Psychiatry, 47, 224-227.
Owens, M., Stevenson, J., & Hadwin, J.A. ( 2012). Anxiety and depression in academic performance: an exploration of the mediating factors of worry and working memory. School Psychology Interntional, 50(2), 180–190.
Qureshi, S. U., Long, M. E., Bradshaw, M. R., Pyne, J. M., Magruder, K. M., Kim-brell, T., & et al. (2011). Does PTSD impair cognition beyond the effect oftrauma?. The Journal of Neuropsychiatry and Clinical Neurosciences, 23, 16–28.
Schuitevoerdera,S., Jay, W., Rosen, J. W., Twamleyc, E. W., Sones, H., Ayersa,C. R., Heather,S., Lohr, J. B., Goettera, E. M., Greg, A. F., Kathryn, H., & Thorp, S. R. (2013). A meta-analysis of cognitive functioning in older adults with PTSD. Journal of Anxiety Disorders, 27, 550– 558.
Sharifi ,V., Asaadi, M., Mohammadi, M. R., Amini, H., Kavyani, H., Semnano, Y., et al. (2009). Reliability and functionality ofthe Persian version of the structured diagnosticinterview for DSM-IV. New Journal of CognitiveScience, 4,1_2.[Persian].
Sharifi, A., H., Zainab. (2009). A comparative study of depression in adolescents. Nursing and Midwifery, 7, 12-8.[Persian].
Siegle GJ, Ingram RE, Matt GE. Affective interference: an explanation for negative attention biases in
Tarbuck, A. F. & Paykel, E. S. (1995). Effects of major depression on the cognitive function of younger and older subjects. Psychological Medicine, 25, 285±295.
TSOURTOS, G., THOMPSON, J. C., & STOUGH, C. (2002). Evidence of an early information processing speed defcit in unipolar major depression. Psychological Medicine, 32, 259±265.
Twamley, E. W., Allard, C. B., Thorp, S. R., Norman, S. B., Hami-Cissell, S., Hughes-Berardi, K., & et al. (2009). Cognitive impairment and functioning in PTSD related tointimate partner violence. Journal of the International Neuropsychological Society,15, 879–887.
Vasterling, J. J., Duke, L. M., Brailey, K., Constans, J. I., Allain, A. N., & Sutker, P. B. (2002).Attention, learning, and memory performances and intellectual resources inVietnam veterans: PTSD and no disorder comparisons. Neuropsychology, 16,5–14
Weiss, D., & Marmar, C. (1997). The Impact of Event Scale Revised. In J. Wilson & T. Keane
(Eds.), Assessing psychological trauma and PTSD. New York: Guildford.
Yasik, A. E., Saigh, P. A., Oberfield, R. A., Halamandaris, P. V. (2007). Posttraumatic stress disorder: memory and learning performance in children and adolescents.Biol Psychiatry, 61(3):382-8.