تاثیر تحریک الکتریکی مستقیم قشر خلفی‌خارجی و شکمی‌میانی پیش‌پیشانی بر بهبود ارزش آینده در کودکان با اختلال نقص‌توجه-بیش‌فعالی

نویسندگان
دانشگاه شهیدبهشتی
چکیده
کودکان مبتلا به اختلال نقص ­توجه و بیش ­فعالی پاداش کوچک­تر اما فوری را به پاداش بزرگ­تر و در آینده ترجیح می ­دهند که این امر منجر به تصمیم ­گیری و رفتارهای تکانشی در آن­ها می ­شود. هدف از پژوهش حاضر بررسی تاثیر تحریک الکتریکی مستقیم قشر خلفی خارجی و شکمی میانی پیش ­پیشانی برای بهبود ارزش آینده در کودکان مبتلا به اختلال نقص ­توجه و بیش ­فعالی بود. در این پژوهش 20 کودک مبتلا به بیش­ فعالی و نقص­ توجه با روش نمونه­ گیری در دسترس انتخاب شدند و هر کدام از آزمودنی­ ها در سه موقعیت تحریک آندی قشر خلفی­ خارجی پیش ­پیشانی و مهار قشر شکمی میانی پیش ­پیشانی، الگوی معکوس این تحریک و در نهایت در شرایط شبه تحریک از طریق آزمون اثر دیرکرد پاداش مورد ارزیابی قرار گرفتند. یافته­ ها نشان داد که تفاوت معناداری بین عملکرد آزمودنی­ ها در آزمون اثر دیرکرد پاداش در موقعیت­ های مختلف تحریک وجود دارد0/05 > p و تحریک آند بر قشر شکمی ­میانی پیش ­پیشانی ارزش آینده را به­ طور معناداری بهبود می­ بخشد.
کلیدواژه‌ها

عنوان مقاله English

Effect of transcranial Direct Current Stimulation (tDCS) on DLPFC and VMPFC on Improvement of delay discounting in children with Attention Deficit and Hyperactivity Symptoms

نویسندگان English

Azin Sarraj Khorrami
Vahid Nejati
Shahid Beheshti University
چکیده English

Children with ADHD symptoms prefer smaller and immediate gain rather than bigger and long-term ones. This problem would result in impulsive behaviors and decision making. The aim of this study was to show the effect of transcranial Direct Current Stimulation (tDCS) on DLPFC and VMPFC on Improvement of delay discounting in children with Attention Deficit and Hyperactivity Symptoms.In this study, 20 children with hyperactivity and attention deficit symptoms were selected by available sampling method and each of the subjects participated in three montages including anodal/cathodal tDCS on dorsolateral prefrontal cortex and ventral medial prefrontal cortex, the reversed montage, and sham stimulation condition and assessed by delay discounting task. The findings show that there is significant difference in the performance of the subjects in the delay discounting task which was performed on different stimulation positions p<0/05 and anodal stimulation of VMPFC significantly improved delay discounting.

کلیدواژه‌ها English

transcranial stimulation
delay discounting
ADHD
Baker, F., Johnson, M. W., & Bickel, W. K. (2003). Delay discounting in current and never-before cigarette smokers: similarities and differences across commodity, sign, and magnitude. Journal of abnormal psychology, 112(3), 382
Chan, R. C., Shum, D., Toulopoulou, T., & Chen, E. Y. (2008). Assessment of executive functions: Review of instruments and identification of critical issues. Archives of clinical neuropsychology, 23(2), 201-216.
Coffman, B. A., Clark, V. P., & Parasuraman, R. (2014). Battery powered thought: enhancement of attention, learning, and memory in healthy adults using transcranial direct current stimulation. Neuroimage, 85, 895-908.
Conners, C. K., Erhardt, D., & Sparrow, E. P. (1999). Conners' adult ADHD rating scales (CAARS): technical manual.
De Wit, H. (2009). Impulsivity as a determinant and consequence of drug use: a review of underlying processes. Addiction biology, 14(1), 22-31.
Fregni, F., Orsati, F., Pedrosa, W., Fecteau, S., Tome, F. A., Nitsche, M. A., . . . Boggio, P. S. (2008). Transcranial direct current stimulation of the prefrontal cortex modulates the desire for specific foods. Appetite, 51(1), 34-41.
Frost, R., & McNaughton, N. (2017). The neural basis of delay discounting: A review and preliminary model. Neuroscience & Biobehavioral Reviews, 79, 48-65.
Grafman, J., & Litvan, I. (1999). Importance of deficits in executive functions. The Lancet, 354(9194), 1921-1923.
He, Q., Chen, M., Chen, C., Xue, G., Feng, T., & Bechara, A. (2016). Anodal stimulation of the left DLPFC increases IGT scores and decreases delay discounting rate in healthy males. Frontiers in psychology, 7, 1421.
Hecht, D., Walsh, V., & Lavidor, M. (2013). Bi-frontal direct current stimulation affects delay discounting choices. Cognitive neuroscience, 4(1), 7-11.
Kirby, K. N., Petry, N. M., & Bickel, W. K. (1999). Heroin addicts have higher discount rates for delayed rewards than non-drug-using controls. Journal of Experimental psychology: general, 128(1), 78.
Martinelli, M. K., Mostofsky, S. H., & Rosch, K. S. (2017). Investigating the impact of cognitive load and motivation on response control in relation to delay discounting in children with ADHD. Journal of abnormal child psychology, 45(7), 1339-1353.
Mazur, J. E. (1987). An adjusting procedure for studying delayed reinforcement. Commons, ML.; Mazur, JE.; Nevin, JA, 55-73.
McDonald, S. (2013). Impairments in social cognition following severe traumatic brain injury. Journal of the International Neuropsychological Society, 19(3), 231-246.
Nitsche, M. A., & Paulus, W. (2011). Transcranial direct current stimulation–update 2011. Restorative neurology and neuroscience, 29(6), 463-492.
Roiser, J. P., & Sahakian, B. J. (2013). Hot and cold cognition in depression. CNS spectrums, 18(3), 139-149.
Sadock, B., & Sadock, V. (2015). Kaplan & Sadock's synopsis of psychiatry behavioral sciences/clinical psychiatry.
Scibinetti, P., Tocci, N., & Pesce, C. (2011). Motor creativity and creative thinking in children: The diverging role of inhibition. Creativity Research Journal, 23(3), 262-272.
Shahbabaie, A., Golesorkhi, M., Zamanian, B., Ebrahimpoor, M., Keshvari, F., Nejati, V., . . . Ekhtiari, H. (2014). State dependent effect of transcranial direct current stimulation (tDCS) on methamphetamine craving. International Journal of Neuropsychopharmacology, 17(10), 1591-1598.
Simpson, C. A., & Vuchinich, R. E. (2000). Reliability of a measure of temporal discounting. The Psychological Record, 50(1), 3-16.
Stagg, C. J., & Nitsche, M. A. (2011). Physiological basis of transcranial direct current stimulation. The Neuroscientist, 17(1), 37-53.
Utz, K. S., Dimova, V., Oppenländer, K., & Kerkhoff, G. (2010). Electrified minds: transcranial direct current stimulation (tDCS) and galvanic vestibular stimulation (GVS) as methods of non-invasive brain stimulation in neuropsychology—a review of current data and future implications. Neuropsychologia, 48(10), 2789-2810.
Volz, K. G., & von Cramon, D. Y. (2009). How the orbitofrontal cortex contributes to decision making—a view from neuroscience. Progress in brain research, 174, 61-71.
Willcutt, E. G., Doyle, A. E., Nigg, J. T., Faraone, S. V., & Pennington, B. F. (2005). Validity of the executive function theory of attention-deficit/hyperactivity disorder: a meta-analytic review. Biological psychiatry, 57(11), 1336-1346.