طراحی پروتکل نوروفیدبک و اثربخشی آن بر تکانشگری، بی ثباتی هیجانی و رفتار جرح خویشتن در بیماران مبتلا به اختلال شخصیت مرزی

نویسندگان
1 دانشگاه رازی
2 دانشگاه علوم پزشکی مازندران
چکیده
اختلال شخصیت مرزی اختلالی با یک الگوی فراگیر بی ثباتی در روابط بین فردی، خودانگاره و عواطف به همراه تکانشگری بارز است. این اختلال با نقص مدارهای فعالیت فرونتالی مشخص شده است که نقش مهمی را در بازداری و تنظیم پرخاشگری بازی می کنند. پژوهش حاضر با هدف طراحی پروتکل نوروفیدبک و بررسی اثربخشی آن بر تکانشگری، بی ثباتی هیجانی و رفتار جرح خویشتن در بیماران مبتلا به اختلال شخصیت مرزی انجام شد. پژوهش نیمه آزمایشی بوده که با طرح پیش آزمون – پس آزمون و دوره پیگیری با گروه گواه اجرا شد. نمونه پژوهش شامل 30 بیمار مبتلا به اختلال شخصیت مرزی بودند که با توجه به تشخیص روانپزشک و با استفاده از مصاحبه بالینی ساختارمند بر اساس DSM5 ، تشخیص اختلال شخصیت مرزی را دریافت کردند. آنها با نمونه گیری در دسترس انتخاب و به به صورت تصادفی به دو گروه تجربی (آموزش نوروفیدبک) و کنترل تقسیم شدند .گروه آزمایش تحت 30 جلسه آموزش نوروفیدبک قرار گرفتند و گروه گواه در لیست انتظار قرار گرفتند. پس از آخرین جلسه درمانی، هردو گروه مجددا ارزیابی شدند. از مقیاس اختلال شخصیت مرزی(STB، پرسشنامه تکانشگری بارات(1957)، پرسشنامه بدتنظیمی هیجانی گراتز و رومر( 2004)، مقیاس خودآسیبی(سوانسون و همکاران، 1998) برای ارزیابی استفاده شد. سه ماه بعد از اجرای پژوهش آزمودنی ها مجددا مورد پیگیری قرار گرفتند . داده ها یا تحلیل کواریانس، تحلیل کوواریانس چندمتغیر( مانکووا) و تحلیل واریانس با اندازه گیری تکراری تحلیل شدند. یافته ها نشان داد که پس از کنترل اثر پیش آزمون، آموزش نوروفیدبک تاثیر معنی داری در کاهش علایم تکانشگری، بی ثباتی هیجانی و مولفه های آن و همچنین رفتار جرح خویشتن در گروه آزمایشی به نسبت گروه کنترل داشت(000/0=p). با توجه به یافته ها می توان گفت روش آموزش نوروفیدبک به عنوان یک روش موثر در کاهش تکانشگری، بی ثباتی هیجانی و رفتار جرح خویشتن قابلیت کاربرد اجرایی در مراکز درمانی را دارد.
کلیدواژه‌ها

عنوان مقاله English

The Design of neurofeedback protocol and it’s effect on impulsivity, emotional instability, self-mutilation behavior in patient with borderline personality disorder (BPD)

نویسندگان English

Fereshte Bakhshian 1
Kamran Yazdanbakhsh 1
Jahangir Karami 1
Seyed Hamze Hoseini 2
1 Razi University
2 Mazandaran University of Medical Sciences
چکیده English

Borderline personality disorder is a disorder with a pervasive pattern of instability in interpersonal relationships, self-image, and emotions with impulsivity. This disorder is characterized by defects in the frontal activity circuits that play an important role in inhibiting and aggression regulation. The aim of this study is to design a neurofeedback protocol and investigate its effect on impulsivity, emotional instability and self-mutilation behavior in patients with borderline personality disorder. This study is a quasi-experimental study with a pre-test, post-test, follow up and control group design. The research sample consisted of 30 patients with borderline personality disorder that received a diagnosis of borderline personality disorder according to the diagnosis of a psychiatrist and a structured clinical interview based on DSM5. They were selected by available sampling and divided into experimental (neurofeedback training) and control groups randomly. The experimental group underwent 30 sessions of neurofeedback training and the control group was placed on a waiting list.

After the last treatment session, both groups were re-evaluated. To collect the data, The Borderline Personality Disorder Scale (STB), Barat Impulsivity Questionnaire (1957 Difficulties in Emotion Regulation Scale (Gratz and Roemer ,2004), and the Self-injury Scale (Swanson et al., 1998) were used. Three months after the study, the subjects were followed up again . The results showed that after controlling the effect of pretest, neurofeedback training had a significant effect on reducing the impulsivity, emotional instability and its components, as well as self-mutilation behavior in the experimental group compared to the control group(p<0/001(. With regard these results, we can say that the neurofeedback training method is an effective way to reduce the impulsivity, emotion dysregulation, and self-mutilation behavior in the treatment centers.

کلیدواژه‌ها English

Neurofeedback
impulsivity
emotional instability
self-mutilation behavior
borderline
Alavi, Kh. (2010). The effectiveness of group dialectical behavior therapy in reducing students' depressive symptoms. Master Thesis. Mashhad Ferdowsi University [Persian]
American Psychiatric Association. (2013). Diagnostic and Statistical Manual of Mental Disorders. American Psychiatric Press, Washington DC.
Azaranfi, D., Rahmanian, M. (2013). Getting started with Neurofeedback. Tehran: Danjhe
Basharpoor,S, Toloi Mehmandoostolya, A,Narimani, M , Atadokht, A (2014), Relation of Emotion Processing Styles and Alexithymia with Symptoms of Borderline Personality Disorder, J Babol Univ Med Sci; 16(7),55-62[Persian]
Bearden CE., Hoffman KM., Cannon TD. (2001) The neuropsychology and neuroanatomy of
bipolar affective disorder: a critical review. Bipolar Disord; 3:106-50.
Brodsky, B.S., Groves, S.A., Oquendo, M.A., Mann, J.J., Stanley, B. (2006). Interpersonal precipitants and suicide attempts in borderline personality disorder. Suicide Life Threat. Behav. 36, 313–322
Brown, M. Z., Comtois, K. A., & Linehan, M. M. (2002). Reasons for suicide attempts and nonsuicidal self-injury in women with borderline personality disorder. Journal of Abnormal Psychology, 111, 198-202
Carli, V., Jovanović, N., Podlesek, A., Roy, A., Rihmer, Z., Maggi, S., Marusic, D., Cesaro, C., Marusic, A., Sarchiapone, M. (2010). The role of impulsivity in self-mutilators, suicide ideators and suicide attempters - a study of 1265 male incarcerated individuals. J. Affect. Disord. 123, 116–122.
Chalbianlu,GR., Abdi,R. (2014), The role of frontal alpha and temperament dimensions in predicting interpersonal problems in patients with borderline personality disorder by mediating emotional differentiation ability, Psychological methods and models,5:17,93-111[Persian]
Chiesa, M., Martino, F., Pozzi, E. (2010). Psychosocial treatment refusal in personality disorder: a comparative study. Personal. Ment. Health 4, 64–74.
Crowell,S.E., Beauchaine,T.P. and Linehan,M.M. (2009). A Biosocial Developmental Model of Borderline Personality: Elaborating and Extending Linehan’s Theory. Psychological Bulletin,135, 495–510.
Davidson RJ. (2004) What does the prefrontal cortex "do" in affect: perspectives on frontal EEG asymmetry research. Biological psychology. 67, 219-23.
Dias, A. M. & van Deusen, A. (2011). “A new neurofeedback protocol for depression”.Span J Psychol, 14(1), 374-384
--Doppelmayr, M.; Nosko, H.; Pecherstorfer, T., Fink, A. (2007). An Attempt to Increase Cognitive Performance After Stroke with Neuro feedback. Biofeedback, 35(4), 126–30.
Douzenis, A., sopelas, C., zeferakos, G. (2012). Medical comorbidity of cluster B personality disorders. Curr. Opin. Psychiatry 25, 398–404.
Etkin, A. (2012). Neurobiology of anxiety: from neural circuits to novel solutions? Depression and Anxiety, 29(5), 355-358.
- Haller, S., Kopel, R., Jhooti, P., Haas,T., Scharnowski, F., Lovblad K. (2013) Dynamic reconfiguration of human brain functional networks through neurofeedback. NeuroImage; 81(1):243-52.
Hammond, D. C. (2011). “What is Neurofeedback: An Update”. Journal of Neurotherapy, 15(4), 305-336.
Hashemian, P. (2015). “The Effectiveness of Neurofeedback Therapy in Craving of Methamphetamine Use”.Open Journal of Psychiatry, 5 (02), 177.
Klimesch, W.; Sauseng, P., Hanslmayr, S. (2007). EEG alpha oscillations: The inhibition–timing hypothesis. Brain Res Rev, 53, 63–88.
Links, P.S., Heslegrave, R., Van Reekum, R. (1999). Impulsivity: core aspect of borderline personality disorder. J. Personal. Disord. 13, 1–9.
Maleki, L., Bafandeh, H. (2015). “Depression and Treatment of Depression inNeurofeedback”. American Scientific Research Journal for Engineering, Technology, and Sciences (ASRJETS), 9(1), 47-63
Marco (2017), Aggressive behavior and self-harm in borderline personality disorder: The role of impulsivity and emotion dysregulation in a sample of outpatients, Psychiatry Research. 249, (2017) 321–326
Martino, F., Lia, L., Bortolotti, B., Menchetti, M., Monari, M., Ridolfi, M.E., Sanza, M., Sasdelli, A., Berardi, D. (2014). La famiglia del paziente con Disturbo borderline diPersonalità: carico della malattia e interventi destinati ai caregivers. Riv. Psichiatr.49, 199–206.
Martino, F., Menchetti, M., Pozzi, E., Berardi, D. (2012). Predictors of drop-out amonpersonality disorders in a specialist outpatients psychosocial programme. A preliminary study. Psychiatry Clin. Neurosci. 66, 180–186.
Moriyama, T. S.; Polanczyk, G.; Caye, A.; Banaschewski, T.; Brandeis, D., & Rohde, L. A. (2012). “Evidence-based information on the clinical use of neurofeedback for ADHD”. Neurotherapeutics, 9(3), 588-598.
Nejati, V., Maleki, G. (2012). The Relationship between Impulsive and Reflective Problem-Solving Behavior. Zahedan J Res Med Sci (ZJRMS); 14(1): 76-81[Persian]
- -Peeters F., Oehlen M., Ronner J., van Os J., Lousberg, R. (2014). Neurofeedback as a treatment for major depressive disorder: a pilot study. Plos One. 9(3),918-37.
Raymond, Joshua, Varney, Carolyn, Parkinson, Lesley A., Gruzelier, John H. (2005) The effects of alpha/theta neurofeedback on personality and mood, Cognitive Brain Research. 23, 287– 292
Rostami, R.,  Dehghani-Arani, F. (2015). “Neurofeedback Training as a New Method in Treatment of Crystal Methamphetamine Dependent Patients : A Preliminary Study”. Applied psychophysiology and biofeedback, 1-11.
Sadat Madani,A., Heydari nasab, L., Yaghubi, H. (2014). investigation of the effectiveness of neurofeedback in reducing the symptoms of hyperactivity and impulsivity in adults with attention deficit / hyperactivity disorder. Scientific-Research Quarterly of Shahed University. 21:11, 85-98, [persian]
-Sansone RA., Wiederman MW., Sansone LA. (1998). The Self-Harm Inventory (SHI): development of a scale for identifying self-destructive behaviors and borderline personality disorder. Journal of clinical psychology, 54(7),973-83.
Seilsepour, M., Hamounpeyma, E., Pirkhaefi, A. (2015). The effect of Neurofeedback therapy sessions on female elementary students with attention deficit and Hyperactivity in Varamin city,2013. Journal of Student Research Committee. 18,60. 24-33, [persian]
Skodol, A.E., Gunderson, J.G., McGlashan, T.H., Dyck, I.R., Stout, R.L., Bender, D.S., Grilo, C.M., Shea, M.T., Zanarini, M.C., Morey, L.C., Sanislow, C.A., Oldham, J.M. (2002). Functional impairment in patients with schizotypal, borderline, avoidant, or obsessive-compulsive personality disorder. Am. J. Psychiatry 159, 276–283.
-Soloff, P.H., Lis, J.A., Kelly, T., Cornelius, J., Ulrich, R. (1994). Risk factors for suicidal behavior in borderline personality disorder. Am. J. Psychiatry 151, 1316–1323.
Surmeli, T., Ertem, A. (2009). “QEEG Guided Neurofeedback Therapy in Personality Disorders: 13 Case Studies”. Clinical EEG and Neuroscience, 40(1), 5-10.
Terzi, L., Martino, F., Berard, D., Bortolott, B., Sasdell, A., Menchett, Linehan,M.M.(1993). Cognitive Behavioral Treatment of Borderline Personality Disorder. New York: Guilford.
Tuladhar, A. M.; ter Huurne, N.; Schoffelen, J. M., Maris, E.; Oostenveld, R., Jensen, O. (2007). Parieto occipital sources account for the increase in alpha activity with working memory load. Hum. Brain Mapp, 28, 785–792.
Vernon, D. J. (2005). “Can neurofeedback training enhance performance? An evaluation of the evidence with implications for future research”.Applied Psychophysiology and Biofeedback, 30(4), 347-364.
Ynu SM., Kwack YS. (2015). The treatment effect of neurofeedback training on executive function in attention – deficit hyperactivity disorder. J Korean Acad Child Adolesc Psychiat;26(1),45-51.
-Zanarini, M.C. (1993). BPD as an impulse spectrum disorder. In: Paris, J. (Ed.), borderline personality disorder: Etiology and Treatment. American Psychiatric Press, Washington, DC, 67–85.