Investigating the effectiveness of cognitive rehabilitation intervention on executive functions (problem solving style, memory) and reducing depression in patients with immunodeficiency (HIV)

Authors
Mohsen Jalali
Amineh Khedmati Nojeh Deh Sadat
Ahmad Torabi
maryam Naderi
Abstract
HIV is associated with extensive physical and psychological consequences, significantly affecting the quality of life of patients. Cognitive rehabilitation is a novel intervention aimed at improving cognitive and psychological functioning in these individuals. The present study aimed to evaluate the effectiveness of cognitive rehabilitation intervention on reducing depression, improving working memory, and enhancing attention in patients with immune deficiency. This quasi-experimental study utilized a pretest-posttest control group design and was conducted in Izeh, Iran, in 2023. A total of 30 patients with HIV were selected through purposive sampling and randomly assigned to experimental and control groups (15 participants per group). Instruments included the Beck Depression Inventory, Working Memory Assessment, and Continuous Performance Test to measure attention. The experimental group underwent 12 sessions of cognitive rehabilitation (60 minutes each, three times a week), while the control group received no intervention. Posttests were administered to both groups after the intervention. Data were analyzed using multivariate covariance analysis (MANCOVA) in SPSS.23. The results showed that cognitive rehabilitation significantly reduced depression and improved working memory and attention in the experimental group compared to the control group (P ≤ 0.001). These findings suggest that cognitive rehabilitation is an effective approach for enhancing cognitive and psychological outcomes in patients with immune deficiency and can be utilized in therapeutic settings.
Keywords
cognitive rehabilitation
depression
working memory
Attention
Immune deficiency
HIV
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